Robert A. Bellantone, Ph.D. 

Robert Bellantone is a founding member of Physical Pharmaceutica LLC, and currently serves as its President, Treasurer and Chief Scientific Officer, overseeing all scientific and technical activities.  He also holds the designation of Professor Emeritus at Long Island University. 


Dr. Bellantone holds a B.S. in pharmacy and Ph.D. in physics, and also completed all of the Ph.D. courses in pharmceutics, all at the University of Connecticut. He is an expert in the areas of formulation material science, in vitro release test methods, biopharmaceutics and pharmacokinetics, and computational methods. He has developed novel drug delivery technologies and numerous in vitro release test (IVRT) methods for evaluation of complex dosage forms, and has received five U.S. patents (with two others pending). He is also a consultant to the pharmaceutical industry and serves as an expert witness in patent litigations in formulation science and pharmacokinetics. 


In 2016, Dr. Bellantone  retired as a full professor from the College of Pharmacy at Long Island University, where he taught and performed research for nearly 20 years. He served as major adviser to 27 Ph.D. graduates and currently serves as major adviser for two current Ph.D. students. He is the author or co-author of over 100 peer reviewed research articles and presentations, and the author of a book chapter on amorphous solids. He has presented his research numerous times at the U.S. Food and Drug Administration, on such topics as pulsatile microdialysis (PMD), in vitro release test methods for complex ophthalmic formulations such as emulsions, and nanoparticle dissolution. He has also has  presented at numerous conferences and pharmaceutical companies. He can be reached at 


Jean B. Mauro, J.D.

Jean Mauro is a founding member and is the Vice President and Secretary of Physical Pharmaceutica LLC.  He also serves as the Legal and Intellectual Property Counsel.  He holds a B.Engineering in Chemical Engineering from Yale University, an M.B.A. from New York University, and a J.D. from the University of Maryland.  He has practiced Intellectual Property law for over 45 years, and created the winning strategy in one of the most cited of patent appellate litigations.  Prior to retiring from industrial practice, he served for nearly 20 years at Union Carbide, where he was Managing Patent Counsel for two of its largest corporate divisions, across a wide array of products and business areas, both in the United States and internationally.  Before entering the legal profession, he was involved in extensive organic chemical research at DuPont and subsequently as Technology Assistant to a Corporate Vice President at Olin Corp.  He has been a contributing author to  the encyclopedia “The Science and Technology of Polymer Films” (Wiley-Interscience), and is a named inventor on several U.S. patents.  He has  long been active in pro bono work, is a founding trustee of three non-profit corporations and a founder of two charitable funds.  Mr. Mauro can be reached at


Piyush G. Patel, Ph.D.

Piyush Patel serves as a Principal Scientist at Physical Pharmaceutica LLC. He is an expert in solid dispersions and nanoparticles, and evaluating the supersaturated solutions that they produce. He is an expert in the application of pulsatile microdialysis (PMD) for evaluating drug dissolution/release from supersaturating and complex dosage forms, and for evaluating the effects of food-drug interactions on drug dissolution. He has also worked on the effects of water-excipient interactions, and has published in the areas of solid dispersions and supersaturated solutions. Dr. Patel can be reached at


Kosha B. Shah, Ph.D.

Kosha Shah serves as a Principal Scientist at Physical Pharmaceutica LLC. She has experience developing methods to characterize supersaturated solutions, including the kinetics of drug nucleation and precipitation (spring and parachute effects). She is an expert in the application of pulsatile microdialysis (PMD) for evaluating drug dissolution/release from supersaturating and complex dosage forms, and for determining the drug distribution in complex dosage forms such as creams, microemulsions, and liposomes. She has also worked in the area of evaluating the effects of food-drug binding interactions on drug dissolution. She has published research in the area of supersaturated solutions. Dr. Shah can be reached at

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