What is PMD?
PMD is an innovative technology that is owned by Physical Pharmaceutica, which offers unique characterization and analytical capabilities that are not available with other technologies. Over 15 years of research and development have led to five awarded patents and unique, leading edge technical expertise that is at the forefront of studying drug release from complex systems (nanoparticles, microemulsions, liposomes, and others) and the fate of supersaturated drug solutions (the dissolved free concentration .
PMD provides accurate and reproducible data, and is used to determine the dissolved free drug concentration in media. It is particularly advantageous for performing studies of systems that are heterogeneous on the micro and macro scales, can be implanted in systems for in situ sampling. For many systems, PMD provides data that no other technology can provide. For instance, drug concentrations in complex media can be determined as often as every 15 seconds, which is a time resolution that is unmatched by any other technology.
Applications of PMD
PMD has been used to study dozens of systems, including: